simparica trio for dogs side effects

Im beside myself. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. My dogs have been throwing up since then and I could not for the life of me figure out why. Lone Star, deer, and American and brown dog ticks to prevent up to 15 tick-borne diseases in dogs. Youre an idiot then! This medicine is making her shaky/tremor, anxious, and she is panting a ton. I took him to the emergency hosp. Not sure what effects he will continue to have. No vet writer or qualified reviewer has received any compensation from the manufacturer of the medication as part of creating this article. She is absolutely miserable and we're hoping she makes it. My 3 month old shih tux Juno took her second dose last week and for the last two days shes vomited and has been eating grass nonstop! I feel so bad ,my 8weeks cockerspaniel hasnt been the same 24 hours of giving first dose of Simparica trio.My boy has been distressed with lethargic conditions,sleepy and peeing . (145 Reviews) $15.50 - $31.09. Nexgard can cause lethargy and a loss of appetite in dogs. Not even going to risk it . Just gave my baby her first dose. Eyes roll back. She is lethargic, unsteady on her feet, doesnt bark at all, showing signs of dimentia. Why would he knowingly recommend this? My husband said that he felt like it would just make his coat shiny. Gave my dogs simparica and they both have lost their appetite! Just be aware that no oral tick medicine is safe, all are from the same class of drugs. They could either keep her there for observation or I could take her home to observe her. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). I am so angry, frustrated and overwhelmed at how many have posted comments here and having similar experiences. A month later, he was at doggie daycare and we picked him up and he was panting frantically. I had placed an order with Pet Meds for the prescription before I saw any of these side effects.I will be returning this medication and order Heartgard and not sure what we will do for flea and ticks, since he turns his nos Simparica Trio, e to the Nexgard and we really dont feel safe with our Grandson around the topical or collarAny suggestions? All content contained in this article is sourced from public sources or the manufacturer. Has anyone had a dermatitis issue as a result of Simparica? Omg, this is beyond awful and makes me so worried. Other specific monitoring or routine testing while your pet is on this medication may be recommended by your veterinarian depending on your pet's individual needs. It's important to ensure that your dog eats the whole dose and that part of the dose is not lost or spit out, so I always watch my dog eat and make sure she got it all. Her protein levels dropped to almost nothing and stomach filled with fluid. Gave my 28lb German Spitz her monthly prescibed dose of Simparica. I put him on boiled chicken & rice and got him calmed down. Hope all is well .my dog is 3,ive had him on Simparica trio for about 1.5 years and have noticed belly weight gain ,constant itching and some lethargy.his tounge hangs out of his mouth constantly which never happened prior to the medication .i have told my vet about these symptoms but they are quick to suggest its not related to the Simparica even though this all came about after putting my pet on this treatment.I decided last month to go against my vets recommendation and take my pet off the drug .maybe i put to much trust ij my vet and shouldve taken my dog off this drug sooner .better late then never .anyone suggest a tick and flea treatment less harmful for dogs ?? No this puppy hasnt had seizures and I came to this forum to see other problems with this medicine. She has NEVER done that before. She wanted me to monitor him carefully and wait to see how he did on his next dose of Simparica before continuing to prescribe it. The vet did a nasal lavage under anesthesia and got a lot of mucus. Well, let me tell you: THANK YOU ALL FROM THE BOTTOM OF MY HEART. We had family in for the weekend and he was not himself. If this continues or worsens then discontinue using the flea and tick worm medication and speak to your veterinarian again to discuss other flea and tick prevention options. I will not in good conscience continue to give my three previously healthy dogs anymore Simparica Trio as it causing Gand Mal seizures in my older dog and nausea , vomiting and severe thirst and dehydration. She keeps running through the house as though looking for something. Do not give extra or double doses. Then gave me pills of prednisone for him to take 1 pill twice a day . They keep telling me that she would have been sick from the first pill, not just the 2nd. We did not make the connection until today. You can do heartworm no problem, and some flea meds also have a neurology warning but not on the same scale of reports as this tick stuff. Hi there, my dog has been taking simparica trio for two months. They both got similar issues and this was the only thing they both did. It can also cause seizures and tremors, but those side effects are incredibly rare. My vet never mentioned that puppies under 6months cannot be prescribed this medication. I will not be continuing with this treatment. Mine passed within 24 hours of the first dose. I am so beyond mad, what can I do to get this out of her system and better yet what can we do to get this product off the market. How is your puppy doing? Not drinking any water but drooling and swallowing all the time. Also vets needs to tell the truth!!! In addition to the tremors, have you noticed any . Now her dog is very sick and she has to take the dog to the vet every day in the past week. And yeah he ate today 4 chicken breast and appeared to want it even better. Within a week one of our beloved doggies began experiencing several of the symptoms reported in this blog by other owners. I wish I could get it out of her system. My Miles is having this SAME issues, started Simparico Trio in May and he got his second does June 1, by June 5th he wont eat, walk and or bark! old . But then the first time I increased from 6mg to 12mg (again on advice of the vet) as his weight increased, the tremors got noticably worse and he started stumbling for no reason. He has been resting most of the day so far, thankfully no seizures.. but I promise I will not be giving him the other 2 doses I got from the vet after reading all of the experiences everyone else has had with their animals. We took him to the animal er and they checked his vitals and he was fine. The vets and neurologists say it's not simparica trio - but she was perfectly healthy until that dose was given. She had right sided weakness, with right sided neglect( the inability to process stimuli with impaired spatial recognition ). You ask why they are giving this poison to our furbabies, it's easy. I gave my 15 year old dog this medicine. The vet has reported it (at least she too thinks it came from the drug) and a chiropractor checked her for the possiblility of slipped disc etc and said it's not that. I just wanted them gone and for him to feel better. Thank you all so much!!!! Follow up: my Labradoodle visited the ER on T-Day for 2 hrs. Then on day 5 my poor dog just couldnt move. Gave this to my dogs and now he sleeps all the time and tired and has symptoms now like droopy right side weakness cant blink right eye and drooling like bells palsy. This medication is generally well tolerated in most pets. He was vomiting, had diarrhea, urinating constantly and the very scary part were the uncontrollable tremors. How is ur puppy? By Sunday he is having liquid diarrhea! Today shes acting better, finally, but her back legs are still collapsing and she is weak. Also what are you looking at giving your dog as a seizure medication?? First dose was on 4/1 and 9 days later he was vomiting goop (yellow thick goo), he would drink water and vomit. I gave my sweet little toy poodle Simpaica today, and one hour later this poor dog went from happy and healthy to having a terrible seizure. Even when asked to go for a car ride he didn't respond. His vet doesn't think it has anything to do with the Trifexis but I cannot help but think it IS because he was just fine the day before I gave it to him! Did the tremors ever stop? The king cavalier bichon mix seems to be ok just not eating much if at all. My heart is broken. We have never had issues with him peeing in the house - EVER, and he peed in my office. Got a new GS when the old one died. Vet thinks it may be Addision disease and wants to test for it. At the same time, Simparica Trio is used to prevent heartworm and lungworm disease (both caused by blood worms that infect the heart and blood vessels supplying the lungs). He had a problem with severe biting a few months back and Vet said he most likely allergic to fleas (bites). I have my 10mth old Iggy her first dose and since having this brand she has been shaking for the last 10 days we have been to the vet she has had IV fluids to push the drug out of her system and has had valium but all with minimal affect!!! GAGA-gated channels help to calm nerve transmissions, which sarolaner alters, creating an influx of nerve transmissions. SIMPARICA TRIO (sarolaner, moxidectin, and pyrantel chewable tablets) is a flavored, chewable tablet for administration to dogs 8 weeks of age and older. I am feeding her foods such as spirulina; b12 and a special healing earth in her dinner. They want another blood draw in 3 weeks to see where she is. Best case scenario, he is able to come home, but we aren't there yet. Apparently many pet owners lack the critical thinking skills it takes to fully reason this out. Next day, he was suddenly 1000% worse, would not touch food, could not move. It seems to be clearing up with Rx eye drops. While veterinarians often prescribe medications for off-label uses, your veterinarian will determine whether Simparica is right for your pet. I am so worried about her! The seizure has finally stopped and he seems to be sleeping peacefully. Is it effective? Ive spent over $3,000 on vet bills for at least four visits to the ER and follow up lab work including X-rays. Eat grass and vomit. Hes very lethargic and constant vomiting! Pyrantel Pamoate was first approved in 1977 for the treatment and . Hi, we did a spinal tap and MRI, its not viral or bacterial, its called steroid responsive meningitis which essentially is the meninges inflaming on their own, but if you look in this thread youll see others reporting similar symptoms/diagnosis so I do think Simparica trio triggered/caused it. This Tuesday the 17th I had given my dog simparica trio for 27lbs dose. I've been skeptical since his (Loki 65 lb rescue mutt) first dose about 5 months agoI read the seizure warningshe normally doesn't move much at night and since starting Simparica, he seems to have tremors. The next morning, she had uncontrollable tremors and could not walk without falling down. Pyrantel only treats parasites found in the gastrointestinal tract because it does not absorb well into the bloodstream. As per the vet, Simparica is an excellent flea and tick product that is available in oral form. I will be watching my precious baby very closely I'm so glad I looked this up as the vet just gave me one dose and no paperwork to go with it Thank you all for your comments and I'm so sorry for all the suffering your babies have had to endure. Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. I am both incredibly sad and angry. She hasn't had any of the diarrhea or eating issues, but has had one of her eyes that gets red and the inner eyelid partially covers her pupil. The cost of Simparica Trio generally ranges from $2230 per dose depending on the tablet size, number of doses, and source of purchase. The day after administering drug he had two incapacitating seizures. Head down, facing the wall, tremors, lethargic, and she can't seem to see well. Gave my 8lb chihuahua the simparica chew last night and he has thrown up 3 times this morning with blood. We were so upset - I vowed to never use oral flea treatment again. Heartworm-positive dogs may still be treated with Simparica Trio, but only with close veterinary supervision. We live in Texas and I have only used an isoxazoline preventative when insect populations get out of control in my area, like they are now. I advise all pet owners to know the side effects. Exactly. I hope this comment will save you and your pets from unnecessary trouble. I've had to syringe water in his mouth. Today she has fallen 2 or 3 times in the last 8 hours). When it came time to pick the right product for my own dog, I opted for Simparica Trio. Im done with this drug! All antiparasitics for dogs lower the seizure threshold. Sarolaner is an acaricide (kills ticks and mites) and insecticide (kills fleas) belonging to the isoxazoline class of drugs. . They gave him a strong shot of prednisone that was good for 2 days . Sarolaner is also used in combination products for both dogs and cats. Im just hoping my sweet girl is going to be ok. My English Springer Spaniel(Sadie) received her first dose of Simparica Trio at 12 weeks old, with no noticeable side effects. Blood work + urine sample. - she's had several episodes since then. I hope it has no permanent impact on him. I only researched it after he started not feeling well, just trusted my vet that this was safe. Thannks !! I switched all three of my dogs to simparica trio and ironically my one that is a simi feral h/w+ hound disappeared. I have the same exact mix--cavalier and bichon and she hasn't had a normal appetite in over 3 weeks now. I hope we get to the bottom of it as this is not fun. I have always been apprehensive about putting my dog on Heartworm / Flea Tick medication because of horror stories, but I thought he's 5 and it will be from the vet and it seems like the responsible thing to do. Yesterday one baby threw up four times within one hour of taking her chewable. I have a vet appointment tomorrow to figure it out. Thanks Michelle! I know it's still in her system because I am still finding dead ticks that I miss because they are the size of a sesame seed. If you need to get rid of parasites, spot-on (the one by a German company is effective enough) will do the job and do it safely. I gave 2 of my older Labs a dose of Simparica on a Saturday. We asked our vet, but he ignored the question. Simparica Trio comes with a customer satisfaction guarantee: Zoetis will cover some or all vet expenses should your dog develop heartworm disease, Lyme disease, a flea infestation, hookworms, or roundworms. This past October he just wasn't the same. All three drugs are pesticides that work by attacking the nervous system of the fleas and ticks, causing death. Good luck. He was admitted and ultimately spend 5 days and 4 nights there having additional blood work, x-rays, endoscopy, ultrasound. Simparica is good at killing contagious parasites that cause mange and scabies. We spend last night at the Emergency Vet, and all day today at her normal vet. Were now into day 2 no changes except add a continuous walking into the next room turn around come back sit down just to repeat several more times. They were taking Simperica for flea/tick and Heartguard to prevent heart worms. Also I read on Dr Mercola site that heartworms is in the dogs blood not the digestive track and garlic won't work. If anyone has suggestions or knows how else I can help my little guy please let me know. not eating alor and wants me to rub her tummy constantly . He has no appetite, wont drink water and his mouth is so dry. This can help with feelings of anxiety, stress, and fear." I can not find any information on a delayed reaction AND my Vet just discredits that its the Simparica because my dog goes to Daycare and could be exposed to other mystery things. My one year old has severe diarrhea and is very agitated and anxious. It has been 20 days since I gave her the prescribed dose of Simparica. Took her to her Vet where I was told she had another tremor. and you expect people to give this to their beloved pets? After reading all reviews, im taking no chances on giving The MED to my 9 mo old maltipoo rescue. The FDA considers this level to be "very rare". Yep days ago started vomiting and having seizures. They want $5k to do a spinal tap and MRI. All went well until this morning. Two weeks after first simparica dose.parasites gone. They did an ultrasound (2 of them), X-rays, blood test, gave fluids, did another ultrasound (looking for a master fluid that keeps popping up and going away between her stomach cavity & spinal cord. Use a collar or topical if you need to. . He just isnt himself. Sorry to hear about this happening to so many. The vet told me to switch to Simparica trio after they stopped seeking revolution which he had been on for many years. They still will not consider that it is the Simparica Trio. Vet says garlic doesn't work and obviously it didn't because he shaved a little of dogs fur and put it on a paper towels and it was full of fleas.The vet gives me Simpirica-ok fleas are dropping off him like crazy. He has no appetite. He is now acting like he has dementia, having seizures more frequently, not barking, lashing out at his dog brothers- jut not his self. He's experiencing auto-inmune disease symptoms and we were told he is in critical condition. The risk and consequences of tick paralysis are much higher than the risk of side effects. He is a 89 lbs 5 y/o pitbull who has never had any issues before. The vet said the simparica didn't cause the disease but it could have been the link that pushed him into the Crisis. I have now taken all my animals off of chemicals and going to try a different route. Your pets condition worsens or does not improve with treatment, You have additional questions or concerns about the use of Simparica or Simparica Trio. I will update once we have results from diagnostics.

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